Classification of Streptococci
Lancefield Group
|
Species
|
Hemolysis
|
Associated Diseases
|
Treatment
|
Lancefield Group
|
Species
|
Hemolysis
|
Associated Diseases
|
Treatment
|
A
|
S. pyogenes
|
β
|
Pharyngitis, tonsillitis, wound and skin infections, septicemia, scarlet fever, pneumonia, rheumatic fever, glomerulonephritis
|
Penicillin, erythromycin, clindamycin
|
Necrotizing fasciitis
|
Expeditious surgical management
β-Lactam (usually broad spectrum until etiology is identified; if GABHS is confirmed, penicillin or cefazolin can be used) plus clindamycin
|
|||
B
|
S. agalactiae
|
β
|
Sepsis, postpartum or neonatal sepsis, meningitis, skin infections, endocarditis, septic arthritis, UTIs
|
Penicillin or ampicillin, cephalosporin, vancomycin
|
C and G
|
S. equi, S. canis
|
β
|
Pharyngitis, pneumonia, cellulitis, pyoderma, erysipelas,
impetigo, wound infections, puerperal sepsis, neonatal sepsis,
endocarditis, septic arthritis
|
Penicillin, vancomycin, cephalosporins, macrolides (variable susceptibility)
|
D
|
Enterococcal:
Enterococcus faecalis, E. faecium
Nonenterococcal:
S. bovis, S. equinus
|
α or γ
|
Endocarditis, UTI, intra-abdominal infection, cellulitis, wound infection as well as concurrent bacteremia
|
Penicillin, ampicillin, vancomycin (plus an aminoglycoside for serious infection)
Vancomycin-resistant enterococci: Streptogramins (quinupristin/dalfopristin), oxazolidinones (linezolid), lipopeptide (daptomycin)
|
S. gallolyticus (formerly
S. bovis biotype I)
|
Colonic adenomas or carcinomas
|
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Viridans*
|
S. mutans, S. sanguis, S. salivarius, S. mitior, S. milleri
|
α or γ
|
Endocarditis, bacteremia, meningitis, localized infection, abscesses (particularly
S. milleri)
|
Penicillin, ampicillin, vancomycin (plus an aminoglycoside for serious infection), other antibiotics based on in vitro susceptibility
|
S. suis
|
Meningitis, sometimes toxic shock syndrome
|
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S. iniae
|
Cellulitis, invasive infections from fish
|
Penicillin
|
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*Do not conform to specific serogroups.
|
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GABHS = group A β-hemolytic streptococci.
Source: http://www.merckmanuals.com/professional/infectious-diseases/gram-positive-cocci/streptococcal-infections |
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